Preimplantation Genetic Diagnosis (PGD) is performed by taking a single cell with biopsy from the embryos obtained by IVF and sending it for genetic examination and transferring the normal and intact (in terms of chromosomal and genetic diseases) embryos to the uterus.
It is possible that there is a chromosomal abnormality in embryos, both in early recurrent pregnancies and in unsuccessful IVF trials.
In summary, the times where PGD is applied are:
· -Recurrent pregnancy losses
· -Repeated unsuccessful IVF trials
· -Having a known genetic disease in the family (Thalassemia, Sickle cell anemia etc.)
· -Advanced maternal age
Since embryos are transferred after PGD, chorion biopsy from the placenta (CVS), examination of the baby's water from the placenta (Amniocentesis) and termination of pregnancy due to a chromosomal or genetic disorder can be avoided.